PYRIDO[2,3-d]PYRIMIDIN-7(8H)-ONES AS CDK INHIBITORS

The pyrido[2,3-d]pyrimidin-7(8H)-ones of Formula 1 and pharmaceutical compositions containing compounds of Formula 1 as CDK inhibitors are disclosed herein. Methods and use of a compound of Formula 1 in the treatment of cancer and manufacture are also disclosed.

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Bibliographic Details
Main Authors Sanchez, Juan, Zapatero, Elisabet, Malumbres, Marcos, Alvarez-Fernández, Mónica, Salazar-Roa, María
Format Patent
LanguageEnglish
Published 09.02.2023
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The pyrido[2,3-d]pyrimidin-7(8H)-ones of Formula 1 and pharmaceutical compositions containing compounds of Formula 1 as CDK inhibitors are disclosed herein. Methods and use of a compound of Formula 1 in the treatment of cancer and manufacture are also disclosed.
Bibliography:Application Number: US202217942508