RAPAFUCIN DERIVATIVE COMPOUNDS AND METHODS OF USE THEREOF
The present disclosure provides macrocyclic compounds inspired by the immunophilin ligand family of natural products FK506 and rapamycin. The generation of a Rapafucin library of macrocyles that contain FK506 and rapamycin binding domains should have great potential as new leads for developing drugs...
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Main Authors | , , , , , , , |
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Format | Patent |
Language | English |
Published |
05.01.2023
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Subjects | |
Online Access | Get full text |
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Summary: | The present disclosure provides macrocyclic compounds inspired by the immunophilin ligand family of natural products FK506 and rapamycin. The generation of a Rapafucin library of macrocyles that contain FK506 and rapamycin binding domains should have great potential as new leads for developing drugs to be used for treating diseases. |
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Bibliography: | Application Number: US202017765814 |