ANTI-ICOS ANTIBODIES

• Main Authors: MCCOURT, Matthew John, VAN KRINKS, Cassandra, LEE, E-Chiang, DEANTONIO, Cecilia, KOSMAC, Miha, ALI, Mohammed Hanif, GALLAGHER, Thomas, SANDY, Nikole, GERMASCHEWSKI, Volker, ARKINSTALL, Stephen John, GILLIES, Stephen Douglas, KIRBY, Ian, CAMPBELL, Jamie Iain, SAINSON, Richard Charles Alfred
• Format: Patent
• Language: English
• Published: 01.12.2022
• Subjects: CHEMISTRY; HUMAN NECESSITIES; HYGIENE; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES; MEASURING; MEDICAL OR VETERINARY SCIENCE; METALLURGY; ORGANIC CHEMISTRY; PEPTIDES; PHYSICS; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS; TESTING

Antibodies that bind ICOS (Inducible T cell Co-Stimulator). Therapeutic use of anti-ICOS antibodies for modulating the ratio between regulatory T cells and effector T cells, to stimulate the immune system of patients, including use in treating cancers. Methods of producing anti-ICOS antibodies, incl...