ANTI-ICOS ANTIBODIES

Antibodies that bind ICOS (Inducible T cell Co-Stimulator). Therapeutic use of anti-ICOS antibodies for modulating the ratio between regulatory T cells and effector T cells, to stimulate the immune system of patients, including use in treating cancers. Methods of producing anti-ICOS antibodies, incl...

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Main Authors MCCOURT, Matthew John, VAN KRINKS, Cassandra, LEE, E-Chiang, DEANTONIO, Cecilia, KOSMAC, Miha, ALI, Mohammed Hanif, GALLAGHER, Thomas, SANDY, Nikole, GERMASCHEWSKI, Volker, ARKINSTALL, Stephen John, GILLIES, Stephen Douglas, KIRBY, Ian, CAMPBELL, Jamie Iain, SAINSON, Richard Charles Alfred
Format Patent
LanguageEnglish
Published 01.12.2022
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
TESTING
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Summary:Antibodies that bind ICOS (Inducible T cell Co-Stimulator). Therapeutic use of anti-ICOS antibodies for modulating the ratio between regulatory T cells and effector T cells, to stimulate the immune system of patients, including use in treating cancers. Methods of producing anti-ICOS antibodies, including species cross-reactive antibodies, using transgenic knock-out mice.
Bibliography:Application Number: US202217727288