PROCESS FOR PRODUCING A PHARMACEUTICAL FORMULATION COMPRISING ACTIVE SUBSTANCE, POLYMER AND SURFACTANT

A process for producing a pharmaceutical formulation comprises the steps of:A) suspending a pharmaceutical active substance in an aqueous solution of a polymer;B) drying the mixture obtained in step A);wherein in step A) the pharmaceutical active substance is present in the form of particles having...

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Bibliographic Details
Main Authors OSTENDORF, Michael, DUESENBERG, Bjoern, HOHEISEL, Werner, NUEBOLDT, Christoph
Format Patent
LanguageEnglish
Published 24.11.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A process for producing a pharmaceutical formulation comprises the steps of:A) suspending a pharmaceutical active substance in an aqueous solution of a polymer;B) drying the mixture obtained in step A);wherein in step A) the pharmaceutical active substance is present in the form of particles having a d90 value in the particle size distribution of ≤1 μm and before step B) the pharmaceutical active substance is further contacted with an ionic surfactant.
Bibliography:Application Number: US202017761480