GLUE DEGRADERS AND METHODS OF USE THEREOF

Described herein are glue degrader compounds, their various targets, their preparation, pharmaceutical compositions comprising them, and their use in the treatment or prevention of conditions, diseases, and disorders mediated by various target proteins.

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Bibliographic Details
Main Authors NIMSGERN, Pierre, LACHAL, Julie, CERNIJENKO, Artiom, HORNAK, Viktor, DEWHURST, Janetta, HOLDER, Lauren, KERRIGAN, John Ryan, MANNING, James R, JAIN, Rama, IMASE, Hidetomo, MOREAU, Robert Joseph, MCKAY, Daniel, BECKWITH, Rohan Eric John, HESSE, Matthew James, ZHAO, Junping, YAMADA, Ken, O'BRIEN, Gary, MA, Fupeng, VULPETTI, Anna, JIN, Xianming, BONAZZI, Simone, BUSCHMANN, Nicole, AXFORD, Jake, FAZAL, Aleem, MALIK, Hasnain Ahmed
Format Patent
LanguageEnglish
Published 17.11.2022
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Described herein are glue degrader compounds, their various targets, their preparation, pharmaceutical compositions comprising them, and their use in the treatment or prevention of conditions, diseases, and disorders mediated by various target proteins.
Bibliography:Application Number: US202017642292