PROMOTER REPRESSION
The present invention relates to novel strategies for gradually decreasing the expression of genes by modifying the promoter sequence. Provided are methods for gradually decreasing the expression level of a nucleic acid molecule of interest in a cell, preferably in a plant cell, comprising the step...
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Main Authors | , |
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Format | Patent |
Language | English |
Published |
27.10.2022
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention relates to novel strategies for gradually decreasing the expression of genes by modifying the promoter sequence. Provided are methods for gradually decreasing the expression level of a nucleic acid molecule of interest in a cell, preferably in a plant cell, comprising the step of introducing at least one modification into a promoter sequence, wherein the modification disrupts a core promoter consensus sequence. Furthermore, the invention also provides methods for producing a cell or an organism, preferably a plant cell or a plant, having a decreased expression level of a nucleic acid molecule of interest. The invention also relates to a cell and an organism, preferably a plant cell and a plant, obtained by a method according to the invention. |
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Bibliography: | Application Number: US202017642987 |