MODULATOR OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT, AND PROCESS FOR MAKING THE MODULATOR

Compounds of Formula I:pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the sam...

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Main Authors Cleveland, Thomas, Uy, Johnny, McAuley-Aoki, Rachel, Termin, Andreas P, Abela, Alexander Russell, Krenitsky, Paul John, Alcacio, Timothy, Zhang, Beili, Pierre, Fabrice Jean Denis, Khatuya, Haripada, Hughes, Robert M, Hadida Ruah, Sara Sabina, McCartney, Jason, Frieman, Bryan A, Busch, Brett Bradley, Baek, Minson, Joshi, Pramod Virupax, Paraselli, Prasuna, Van Goor, Fredrick, Zhou, Jinglan, Miller, Mark Thomas, Melillo, Vito, Anderson, Corey, Grootenhuis, Peter, Keshavarz-Shokri, Ali
Format Patent
LanguageEnglish
Published 29.09.2022
Subjects
APPARATUS THEREFOR
CHEMISTRY
GENERAL METHODS OF ORGANIC CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Compounds of Formula I:pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.
Bibliography:Application Number: US202117505699