MICROPARTICLES BASED ON ESTER DERIVATIVES OF HYALURONAN, METHOD OF PRODUCTION, COMPOSITION COMPRISING THEREOF AND USE THEREOF

Microparticles based on ester derivatives of hyaluronan and related methods and compositions are disclosed. The microparticles comprise a conjugate of all-trans retinoic acid and a particular hyaluronan comprising from 1 to 5000 dimer units; where the microparticles comprise a degree of substitution...

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Main Authors PAVLIK, Vojtech, VELEBNY, Vladimir, DOLECKOVA, Iva, BRANDEJSOVA, Martina, ORZOL, Paulina, HUERTA ANGELES, Gloria, NESPOROVA, Kristina, KOPECKA, Katerina, NOVOTNY, Jaroslav
Format Patent
LanguageEnglish
Published 11.08.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC USE OF COSMETICS OR SIMILAR TOILETPREPARATIONS
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Summary:Microparticles based on ester derivatives of hyaluronan and related methods and compositions are disclosed. The microparticles comprise a conjugate of all-trans retinoic acid and a particular hyaluronan comprising from 1 to 5000 dimer units; where the microparticles comprise a degree of substitution of all-trans retinoic acid residues in the conjugate of hyaluronan in the range of from 0.1 to 8%. Methods of preparing the microparticles and related compositions are also disclosed.
Bibliography:Application Number: US202017439284