DICLOFENAC SACHET COMPOSITION

A pharmaceutical composition for oral administration comprising a free-flowing granular powder comprising diclofenac or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable substantially non-hygroscopic water soluble diluent, an optional binder, and one or more optional pharmace...

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Bibliographic Details
Main Authors Trivedi, Jay Sanjay, Ella, Rashmita Duryodhan, Darandale, Sharad Shridhar, Kodgule, Mandar Madhukar
Format Patent
LanguageEnglish
Published 04.08.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:A pharmaceutical composition for oral administration comprising a free-flowing granular powder comprising diclofenac or a pharmaceutically acceptable salt thereof, a pharmaceutically acceptable substantially non-hygroscopic water soluble diluent, an optional binder, and one or more optional pharmaceutically acceptable excipients, wherein the composition is devoid of any alkalizer, buffer or base. The pharmaceutical composition is divided into unit doses containing a therapeutically effective amount of diclofenac, and may be incorporated into sachets, tablets or capsules. and not less than 85% of the free-flowing granulate powder dissolves after 3 minutes in simulated intestinal fluid at pH 6.8. The pharmaceutical composition is rapidly bioavailable when orally administered to a mammal, e.g., human.
Bibliography:Application Number: US202217591333