METHODS AND COMPOSITIONS FOR TREATING EUKARYOTIC INFECTIONS VIA ALTERING AGGREGATION DYNAMICS OF RAPTOR/KOG1
Methods and compositions for activating TORC1 aggregate formation in a fungi or a parasite, wherein TORC1 aggregate formation inhibits growth of the fungi or parasite. TORC1 aggregate formation may be activated using small molecules or other agents, and said agents may be used to treat or prevent a...
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Main Authors | , |
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Format | Patent |
Language | English |
Published |
02.06.2022
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Subjects | |
Online Access | Get full text |
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Summary: | Methods and compositions for activating TORC1 aggregate formation in a fungi or a parasite, wherein TORC1 aggregate formation inhibits growth of the fungi or parasite. TORC1 aggregate formation may be activated using small molecules or other agents, and said agents may be used to treat or prevent a disease or condition associated with the fungi and parasite. The agent may target Kog1 of TORC1, e.g., the agent may directly or indirectly inhibit Kog1 leading to aggregation of the TORC1 complex. |
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Bibliography: | Application Number: US202217671106 |