HTP GENOMIC ENGINEERING PLATFORM FOR IMPROVING FUNGAL STRAINS

A HTP genomic engineering platform for improving filamentous fungal cells that is computationally driven and integrates molecular biology, automation, and advanced machine learning protocols is provided. This integrative platform utilizes a suite of HTP molecular tool sets to create HTP genetic desi...

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Main Authors Bruno, Kenneth S, Vaughan, Dylan, Poust, Sean, Abdulla, Hassan, Boccazzi, Paolo, Cleto, Sara da Luz Areosa, Szewczyk, Edyta, Chaikind, Brian, Westfall, Patrick, SunSpiral, Vytas, Rothschild-Mancinelli, Kyle, Fong, III, Arthur Muir, Fredlund, Jennifer
Format Patent
LanguageEnglish
Published 12.05.2022
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:A HTP genomic engineering platform for improving filamentous fungal cells that is computationally driven and integrates molecular biology, automation, and advanced machine learning protocols is provided. This integrative platform utilizes a suite of HTP molecular tool sets to create HTP genetic design libraries, which are derived from, inter alia, scientific insight and iterative pattern recognition. Methods for isolating clonal populations derived from individual fungal spores are also provided.
Bibliography:Application Number: US202217584950