Fc VARIANTS WITH ALTERED BINDING TO FcRn

The present application relates to optimized IgG immunoglobulin variants, engineering methods for their generation, and their application, particularly for therapeutic purposes.

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Bibliographic Details
Main Authors Chamberlain, Aaron Keith, Yoder, Sean C, Lazar, Gregory Alan, Vielmetter, Jost, Karki, Sher Bahadur, Desjarlais, John R
Format Patent
LanguageEnglish
Published 14.04.2022
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present application relates to optimized IgG immunoglobulin variants, engineering methods for their generation, and their application, particularly for therapeutic purposes.
Bibliography:Application Number: US202117549706