Multivalent and Multispecific DR5-Binding Fusion Proteins

The disclosure relates generally to molecules that specifically engage death receptor 5 (DR5), a member of the TNF receptor superfamily (TNFRSF). More specifically the disclosure relates to multivalent and multispecific molecules that bind at least DR5.

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Bibliographic Details
Main Authors Timmer, John C, Eckelman, Brendan P, Jones, Kyle S, Razai, Amir S, Willis, Katelyn M, Hussain, Abrahim, Deveraux, Quinn
Format Patent
LanguageEnglish
Published 03.03.2022
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The disclosure relates generally to molecules that specifically engage death receptor 5 (DR5), a member of the TNF receptor superfamily (TNFRSF). More specifically the disclosure relates to multivalent and multispecific molecules that bind at least DR5.
Bibliography:Application Number: US202117394900