NEW IMMUNOCYTOKINES FOR THE TREATMENT OF CANCER

The present invention relates to new immunocytokines which are useful for the treatment of cancer. These fusion proteins comprise (i) an antibody or antigen-binding fragment thereof fused to (ii) a cleavable peptide linker, and (iii) cytokine, or functional fragments thereof. Methods of treatment us...

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Bibliographic Details
Main Authors LOWE, Peter, AKLA, Barbara, JANIN-BUSSAT, Marie-Claire, HAEUW, Jean-François, BERTAUX, Céline, CONTET, Alicia
Format Patent
LanguageEnglish
Published 17.02.2022
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present invention relates to new immunocytokines which are useful for the treatment of cancer. These fusion proteins comprise (i) an antibody or antigen-binding fragment thereof fused to (ii) a cleavable peptide linker, and (iii) cytokine, or functional fragments thereof. Methods of treatment using these immunocytokines are also disclosed.
Bibliography:Application Number: US201917280275