IMPLANTABLE DEVICES FOR CELL THERAPY AND RELATED METHODS

Described herein are implantable devices comprising means for mitigating the foreign body response (FBR) and at least one cell-containing compartment which comprises a plurality of cells (e.g., live cells) encapsulated in a polymer composition comprising a cell-binding substance (CBS), as well as co...

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Main Authors Miller, Robert James, Heidebrecht, Richard, Yin, Zoe, Peritt, David, Carmona, Guillaume, Johnston, Erika Ellen, Oberli, Matthias Alexander, Wotton, Paul Kevin, Veiseh, Omid, Barney, Lauren Emily, Beauregard, Michael, Smith, Devyn McKinley, Gonzalez, Francisco Caballero, O'Connor, Owen, Sewell, Jared A
Format Patent
LanguageEnglish
Published 06.01.2022
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Described herein are implantable devices comprising means for mitigating the foreign body response (FBR) and at least one cell-containing compartment which comprises a plurality of cells (e.g., live cells) encapsulated in a polymer composition comprising a cell-binding substance (CBS), as well as compositions and methods of making and using the same. The cells are capable of expressing a therapeutic agent useful for the treatment of a disease, disorder, or condition described herein.
Bibliography:Application Number: US201917280802