DEVELOPMENT AND PARAMETER ASSESSMENT FOR VERTICALLY ALIGNED PLATINUM WIRE APTASENSOR ARRAYS FOR IMPEDIMETRIC DETECTION OF CARDIAC BIOMARKERS
The invention relates to ex-situ biosensors that impedimetrically detect cardiac biomarkers of interest in a bodily fluid sample derived from a patient. The biosensors include a multi-array of vertically aligned platinum wires having immobilized thereon an aptamer that is selected to specifically an...
Saved in:
Main Authors | , |
---|---|
Format | Patent |
Language | English |
Published |
30.12.2021
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The invention relates to ex-situ biosensors that impedimetrically detect cardiac biomarkers of interest in a bodily fluid sample derived from a patient. The biosensors include a multi-array of vertically aligned platinum wires having immobilized thereon an aptamer that is selected to specifically and selectively bind to the cardiac markers of interest. The biosensors are contacted with a portion of the bodily fluid sample, and the aptamer binds to the cardiac markers of interest in the bodily fluid sample. As a result, an electrochemical impedance signal is generated and therefore, a change in electrochemical impedance is indicative of the presence of the cardiac markers of interest in the bodily fluid sample. The biosensors are point-of-care, on-demand devices that can be used in a medical environment, as well as in domestic settings. |
---|---|
Bibliography: | Application Number: US202117471788 |