ANTIBODIES FOR TREATING MALIGNANT TUMORS AND USES THEREOF

Disclosed are an anti-ROR2 antibody and a use thereof. The anti-ROR2 antibody includes at least one of the following: (1) a light chain variable region with amino acid sequence shown in CSASSSVTYTYWYQ, IYDTSNLAS and CQQWSSYPFTFGSG, and a heavy chain variable region with amino acid sequence shown in...

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Main Authors KIPPS, Thomas James, WU, Liufeng, ZHANG, Suping, ZHANG, Jianchao
Format Patent
LanguageEnglish
Published 09.12.2021
Subjects
CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
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Abstract Disclosed are an anti-ROR2 antibody and a use thereof. The anti-ROR2 antibody includes at least one of the following: (1) a light chain variable region with amino acid sequence shown in CSASSSVTYTYWYQ, IYDTSNLAS and CQQWSSYPFTFGSG, and a heavy chain variable region with amino acid sequence shown in YTFTSYLMHWV, LEWIGYINPYNDGTKYNEKFKDKAT and CARSDVYYGVRFAYWGQG; compared with (1), the antibody or antigen-binding fragment has an amino acid sequence with at least one conservative amino acid substitution.
AbstractList Disclosed are an anti-ROR2 antibody and a use thereof. The anti-ROR2 antibody includes at least one of the following: (1) a light chain variable region with amino acid sequence shown in CSASSSVTYTYWYQ, IYDTSNLAS and CQQWSSYPFTFGSG, and a heavy chain variable region with amino acid sequence shown in YTFTSYLMHWV, LEWIGYINPYNDGTKYNEKFKDKAT and CARSDVYYGVRFAYWGQG; compared with (1), the antibody or antigen-binding fragment has an amino acid sequence with at least one conservative amino acid substitution.
Author ZHANG, Suping
ZHANG, Jianchao
WU, Liufeng
KIPPS, Thomas James
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Snippet Disclosed are an anti-ROR2 antibody and a use thereof. The anti-ROR2 antibody includes at least one of the following: (1) a light chain variable region with...
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SubjectTerms CHEMISTRY
INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES
MEASURING
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PHYSICS
TESTING
Title ANTIBODIES FOR TREATING MALIGNANT TUMORS AND USES THEREOF
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