ANTIBODIES FOR TREATING MALIGNANT TUMORS AND USES THEREOF
Disclosed are an anti-ROR2 antibody and a use thereof. The anti-ROR2 antibody includes at least one of the following: (1) a light chain variable region with amino acid sequence shown in CSASSSVTYTYWYQ, IYDTSNLAS and CQQWSSYPFTFGSG, and a heavy chain variable region with amino acid sequence shown in...
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Main Authors | , , , |
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Format | Patent |
Language | English |
Published |
09.12.2021
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Subjects | |
Online Access | Get full text |
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Summary: | Disclosed are an anti-ROR2 antibody and a use thereof. The anti-ROR2 antibody includes at least one of the following: (1) a light chain variable region with amino acid sequence shown in CSASSSVTYTYWYQ, IYDTSNLAS and CQQWSSYPFTFGSG, and a heavy chain variable region with amino acid sequence shown in YTFTSYLMHWV, LEWIGYINPYNDGTKYNEKFKDKAT and CARSDVYYGVRFAYWGQG; compared with (1), the antibody or antigen-binding fragment has an amino acid sequence with at least one conservative amino acid substitution. |
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Bibliography: | Application Number: US202117369989 |