METHODS AND COMPOUNDS FOR PREVENTING AND ARRESTING COVID-19 MORBIDITY AND MORTALITY, VIA INHIBITION OF INTERLEUKIN-6, TNF-ALPHA, AND OTHER CYTOKINES, AND VIA REDUCTION OF C-REACTIVE PROTEINS

Methods and compounds for preventing and arresting COVID-19 morbidity and mortality, via inhibition of Interleukin-6, TNF-alpha, and other cytokines, and via reduction of C-reactive proteins are provided. Analyses of patients with COVID-19 complicated by ARDS, for example, show highly activated cyto...

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Main Authors CHITRE, DEEPA, DEY, DEBENDRANATH, NADKARNI, SATEJ R
Format Patent
LanguageEnglish
Published 04.11.2021
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Summary:Methods and compounds for preventing and arresting COVID-19 morbidity and mortality, via inhibition of Interleukin-6, TNF-alpha, and other cytokines, and via reduction of C-reactive proteins are provided. Analyses of patients with COVID-19 complicated by ARDS, for example, show highly activated cytotoxic T-cells, resulting from hyperactivation of the immune system. A significant surge of Interleukin-6 (IL-6), TNF-α, and other cytokines are thought to be mediators of this enhanced T-cell activity, and runaway inflammation that are dangerous or fatal to the patient. Example oral formulations dubbed BV-4051 and Artovid-20 provide prophylaxis and treatment of these conditions caused by COVID-19 disease. The example formulations contain plant extracts boosting the human immune system and targeting the detrimental effects of the SARS-CoV-2 virus in its various strains.
Bibliography:Application Number: US202117306937