ANTIMICROBIAL COMPOSITIONS COMPRISING CHLORHEXIDINE

Chlorhexidine gluconate is a commonly used disinfectant that is soluble in aqueous solutions. Because it is a common disinfectant, chlorhexidine gluconate is often used in alcohol solvents, but chlorhexidine gluconate is not soluble in C2-05 alcohol solvents. Also, a chlorhexidine gluconate containi...

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Bibliographic Details
Main Authors DIZIO, JAMES P, MENON, VINOD P
Format Patent
LanguageEnglish
Published 30.09.2021
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Chlorhexidine gluconate is a commonly used disinfectant that is soluble in aqueous solutions. Because it is a common disinfectant, chlorhexidine gluconate is often used in alcohol solvents, but chlorhexidine gluconate is not soluble in C2-05 alcohol solvents. Also, a chlorhexidine gluconate containing solution can be susceptible to spontaneous calcium gluconate crystallization when formulated with high levels of solvent such as alcohol. These calcium gluconate crystals appear like glass shards. It is desirable to inhibit the formation of these crystals without affecting the antimicrobial potency of the solution. The disclosed chlorhexidine antimicrobial composition includes a chelating agent to inhibit formation of this salt or reverse crystal formation.
Bibliography:Application Number: US201917270228