AFFINITY CARRIER USING MUTANT VHH ANTIBODY

Provision of an affinity carrier using a mutant VHH antibody. An affinity carrier comprising: a solid phase carrier; and an immunoglobulin-binding protein bound to the solid phase carrier; wherein the immunoglobulin-binding protein comprises a mutant VHH antibody or a fragment of the mutant VHH anti...

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Main Authors ITO, Yuji, MIZUGUCHI, Yusaku, HAGIHARA, Yoshihisa, KIYOSE, Norihiko, MATSUDA, Tomonari, MIYAZAKI, Nobuo, AKAZAWA, Yoko, FUKUTA, Tetsuo
Format Patent
LanguageEnglish
Published 26.08.2021
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:Provision of an affinity carrier using a mutant VHH antibody. An affinity carrier comprising: a solid phase carrier; and an immunoglobulin-binding protein bound to the solid phase carrier; wherein the immunoglobulin-binding protein comprises a mutant VHH antibody or a fragment of the mutant VHH antibody that recognizes an epitope in at least one region selected from the group consisting of amino acids 127 to 184 of SEQ ID NO: 22 and amino acids 13 to 210 of SEQ ID NO: 23.
Bibliography:Application Number: US201917253372