SOLID FORMS OF APOL1 INHIBITOR AND METHODS OF USING SAME

The disclosure provides novel solid state forms of Compound I selected from Form B, citric acid cocrystal Form A, piperazine cocrystal Form A, urea cocrystal Form A, nicotinamide cocrystal Form A, nicotinamide cocrystal Form B, aspartame cocrystal Form A, glutaric acid cocrystal Form A, L-proline co...

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Main Authors PERESYPKIN, Andrey, MEDEK, Ales, MAGUIRE, Courtney, LAI, Mei-Hsiu, GAGNON, Kevin, WITKOS, Faith, SARPAL, Kanika, JUDELSON, Michael, LI, Jicong, SHI, Yi, SHRESTHA, Muna, MINCHOM, Jack, IYEMPERUMAL, Satish Kumar
Format Patent
LanguageEnglish
Published 12.08.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:The disclosure provides novel solid state forms of Compound I selected from Form B, citric acid cocrystal Form A, piperazine cocrystal Form A, urea cocrystal Form A, nicotinamide cocrystal Form A, nicotinamide cocrystal Form B, aspartame cocrystal Form A, glutaric acid cocrystal Form A, L-proline cocrystal Form A, L-proline cocrystal Form B, vanillin cocrystal Form A, and 2-pyridone cocrystal Form A, compositions comprising the same, and methods of using the same, including use in treating APOL1 mediated kidney disease.
Bibliography:Application Number: US202117166927