METHODS OF MEDIATING MACROPHAGE PHENOTYPES

Methods of inducing a polarization of macrophages. The method includes obtaining a blood fraction, fractionating the blood fraction to produce a blood fraction, and contacting the blood fraction with a source of macrophages. A blood fraction including platelet-poor plasma polarizes the source of mac...

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Bibliographic Details
Main Authors Woodell-May, Jennifer E, King, William, Higgins, Joel C
Format Patent
LanguageEnglish
Published 05.08.2021
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Summary:Methods of inducing a polarization of macrophages. The method includes obtaining a blood fraction, fractionating the blood fraction to produce a blood fraction, and contacting the blood fraction with a source of macrophages. A blood fraction including platelet-poor plasma polarizes the source of macrophages into M1 macrophages. A blood faction including a protein solution polarizes the source of macrophages into M2 macrophages.
Bibliography:Application Number: US202117161302