COMBINATION FORMULATION CONTAINING COLCHICINE FOR TREATMENT OR ENHANCING THE THERAPY OF LIVER DISEASE

Exemplary embodiments of the present invention relate to a combination formulation for treatment or enhancing the therapy of liver disease, and more particularly, to a combination formulation prepared by containing colchicine and metformin as main active ingredients.The composition according to exem...

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Bibliographic Details
Main Authors YOON, Ju Ho, CHA, Wang Jo, HAM, Sun Ah
Format Patent
LanguageEnglish
Published 22.07.2021
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Summary:Exemplary embodiments of the present invention relate to a combination formulation for treatment or enhancing the therapy of liver disease, and more particularly, to a combination formulation prepared by containing colchicine and metformin as main active ingredients.The composition according to exemplary embodiments of the present invention may be used as an effective therapeutic agent for liver disease capable of treating and preventing liver fibrosis, liver cirrhosis, liver cancer, or hepatitis by reducing the amount of fat accumulated in the liver tissues by a synergistic effect of colchicine and metformin and lowering glucose tolerance and insulin tolerance and further, may be used as an excellent drug capable of replacing ursodeoxycholic acid.
Bibliography:Application Number: US202017061583