RAS INHIBITORS

The disclosure features macrocyclic compounds, and pharmaceutical compositions and protein complexes thereof, capable of inhibiting Ras proteins, and their uses in the treatment of cancers.

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Bibliographic Details
Main Authors AAY, Naing, PITZEN, Jennifer, BUCKL, Andreas, AGGEN, James, WHALEN, Daniel M, LIU, Yang, CREGG, James, GILL, Adrian L, KOLTUN, Elena S, BURNETT, G. Leslie, KNOX, John E
Format Patent
LanguageEnglish
Published 06.05.2021
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The disclosure features macrocyclic compounds, and pharmaceutical compositions and protein complexes thereof, capable of inhibiting Ras proteins, and their uses in the treatment of cancers.
Bibliography:Application Number: US202017088986