ANTI-GDF-15 ANTIBODIES

Monoclonal antibodies that bind and inhibit the activity of human GDF15 are disclosed. The antibodies can be used to treat body weight loss, including cachexia, associated with the over-expression of human GDF15.

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Bibliographic Details
Main Authors Lerner, Lorena, Chen, Ting, Weng, Zhigang, Tao, Nianjun, Winston, JR., William M, Poling, Laura, Weiler, Solly, Gyuris, Jeno, Abbott, Sandra, Liu, Qing, Bai, Ailin, Chiu, Maria Isabel
Format Patent
LanguageEnglish
Published 08.04.2021
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Summary:Monoclonal antibodies that bind and inhibit the activity of human GDF15 are disclosed. The antibodies can be used to treat body weight loss, including cachexia, associated with the over-expression of human GDF15.
Bibliography:Application Number: US202016824034