STAIN NORMALIZATION FOR AUTOMATED WHOLE-SLIDE IMAGE CLASSIFICATION

Techniques for stain normalization image processing for digitized biological tissue images are presented. The techniques include obtaining a digitized biological tissue image; applying to at least a portion of the digitized biological tissue image an at least partially computer implemented convoluti...

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Bibliographic Details
Main Authors Ianni, Julianna, Soans, Rajath Elias, Sankarapandian, Sivaramakrishnan
Format Patent
LanguageEnglish
Published 25.03.2021
Subjects
CALCULATING
COMPUTER SYSTEMS BASED ON SPECIFIC COMPUTATIONAL MODELS
COMPUTING
COUNTING
HANDLING RECORD CARRIERS
PHYSICS
PRESENTATION OF DATA
RECOGNITION OF DATA
RECORD CARRIERS
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Summary:Techniques for stain normalization image processing for digitized biological tissue images are presented. The techniques include obtaining a digitized biological tissue image; applying to at least a portion of the digitized biological tissue image an at least partially computer implemented convolutional neural network trained using a training corpus including a plurality of pairs of images, where each pair of images of the plurality of pairs of images includes a first image restricted to a lightness axis of a color space and a second image restricted to at least one of: a first color axis of the color space and a second color axis of the color space, such that the applying causes an output image to be produced; and providing the output image.
Bibliography:Application Number: US202017028094