ANTI-CLEVER-1 AGENTS FOR CONTROLLING LYSOSOMAL VATPASE PROTON PUMPS TO INCREASE LYSOSOMAL PH-VALUE AND THE CROSS-PRESENTATION OF DIGESTED MATTER

A method of determining the efficacy of anti-Clever-1 therapy by measuring lysosomal pH, and a method of increasing lysosomal pH for improving an activation of the immune system in a patient, in which method an agent that inhibiting Clever-1 on the lysosomal proton pump (vATPase) is administered to...

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Bibliographic Details
Main Authors VIITALA, Miro, HOLLMÉN, Maija-Leena, RANNIKKO, Jenna
Format Patent
LanguageEnglish
Published 25.03.2021
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:A method of determining the efficacy of anti-Clever-1 therapy by measuring lysosomal pH, and a method of increasing lysosomal pH for improving an activation of the immune system in a patient, in which method an agent that inhibiting Clever-1 on the lysosomal proton pump (vATPase) is administered to a patient.
Bibliography:Application Number: US202017031349