NUCLEOTIDE SEQUENCING ELEMENT AND CHIP, AND SEQUENCING ANALYSIS METHOD

Provided is a nucleotide sequencing element, comprising a semiconductor substrate, a transistor, a dielectric layer, an annular electrode group, and a conductor. Also provided is a nucleotide sequencing chip, comprising the nucleotide sequencing element and a sense amplifier. Also provided is a sequ...

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Bibliographic Details
Main Authors SHIAU, Jeng-Huei, LIEN, Chun-Lung
Format Patent
LanguageEnglish
Published 04.02.2021
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Summary:Provided is a nucleotide sequencing element, comprising a semiconductor substrate, a transistor, a dielectric layer, an annular electrode group, and a conductor. Also provided is a nucleotide sequencing chip, comprising the nucleotide sequencing element and a sense amplifier. Also provided is a sequencing analysis method, comprising: providing the nucleotide sequencing chip as stated above; placing a nucleotide sequence fragment to be tested and a known nucleotide sequence fragment in a slot separately for a polymerization reaction and an electrochemical reaction; and analyzing the electrical signals generated by the reactions to obtain a sequencing result.
Bibliography:Application Number: US201816964193