Erythropoietin and Analogs for Veterinary Use

Provided are various embodiments relating to feline erythropoietin (EPO) polypeptide analogs with one or more additional glycosylation sites and methods of producing and using the same to treat anemia in companion animals. Also provided are various embodiments relating to EPO polypeptides having a m...

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Bibliographic Details
Main Authors Chin, Richard, Li, Yongzhong, Sundlof, Stephen, Chu, Qingyi, Nguyen, Lam, Zhan, Hangjun, Li, Shyr Jiann, Garcia-Murillo, Estela, Leitman, Victoria
Format Patent
LanguageEnglish
Published 04.02.2021
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:Provided are various embodiments relating to feline erythropoietin (EPO) polypeptide analogs with one or more additional glycosylation sites and methods of producing and using the same to treat anemia in companion animals. Also provided are various embodiments relating to EPO polypeptides having a mutation in the second binding site, polypeptides comprising an extracellular domain of EPO receptor, and methods of using the same for treating polycythemia in mammals.
Bibliography:Application Number: US201816617380