A FERMENTATION PROCESS USING YEAST CELLS HAVING DISRUPTED PATHWAY FROM DIHYDROXYACETONE PHOSPHATE TO GLYCEROL

Yeast cells are genetically modified to disrupt a native metabolic pathway from dihydroxyacetone to glycerol. In certain aspects, the yeast cell is of the genera Kluyveromyces, Candida or Issatchenkia. In other aspects, the yeast cell is capable of producing at least one organic acid, such as lactat...

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Bibliographic Details
Main Authors Rush, Brian J, Hause, Benjamin Matthew, Roberg-Perez, Kevin, Suominen, Pirrko, Koivuranta, Kari, Aristidou, Aristos, McMullin, Thomas William, Dundon, Catherine Asleson
Format Patent
LanguageEnglish
Published 03.12.2020
Subjects
CONSTRUCTION OF ROADS, RAILWAYS, OR BRIDGES
CONVEYING
FIXED CONSTRUCTIONS
HANDLING THIN OR FILAMENTARY MATERIAL
MACHINES FOR MAKING RAILWAYS OF ALL KINDS
PACKING
PERFORMING OPERATIONS
PERMANENT WAY
PERMANENT-WAY TOOLS
PNEUMATIC TUBE CONVEYORS
SHOP CONVEYOR SYSTEMS
STORING
TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING ORTIPPING
TRANSPORTING
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Summary:Yeast cells are genetically modified to disrupt a native metabolic pathway from dihydroxyacetone to glycerol. In certain aspects, the yeast cell is of the genera Kluyveromyces, Candida or Issatchenkia. In other aspects, the yeast cell is capable of producing at least one organic acid, such as lactate. The yeast cells produce significantly less glycerol than the wild-type strains, and usually produce greater yields of desired fermentation products. Yeast cells of the invention often grow well when cultivated, despite their curtailed glycerol production.
Bibliography:Application Number: US201815941274