BIOCOMPATIBLE ORGANOGEL MATRICES FOR INTRAOPERATIVE PREPARATION OF A DRUG DELIVERY DEPOT

The present disclosure is directed to an organogel drug depot for use in delivering an active agent to a surgical site, such as an implant site, for instance an orthopedic implant site. The present disclosure is also directed to an organogel drug depot for use in a non-sterile environment and applic...

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Bibliographic Details
Main Authors Bikram-Liles, Malavosklish, Kerr, Sean Hamilton, Florek, Charles, Julien, Junior, Armbruster, David A, Jain, Sanjay
Format Patent
LanguageEnglish
Published 22.10.2020
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:The present disclosure is directed to an organogel drug depot for use in delivering an active agent to a surgical site, such as an implant site, for instance an orthopedic implant site. The present disclosure is also directed to an organogel drug depot for use in a non-sterile environment and application to a non-sterile open wound site. In a further embodiment, there is disclosed a system for preparing an organogel drug depot including an organogel matrix comprising an organogelator and a biocompatible organic solvent, an active agent comprising solid particles, a container including at least one wall having an outer surface and defining a volume capable of containing the organogel matrix and active agent solid particles, and a heating component configured to contact the outer surface and supply an amount of heat to the container.
Bibliography:Application Number: US202016851177