CELL CULTURE METHODS

The present invention relates to methods for reducing the heterogeneity of a population of recombinant proteins produced in cell culture, said methods comprising growing host cells producing a recombinant protein in a cell culture medium wherein the cell culture medium comprises one or more cysteine...

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Bibliographic Details
Main Authors MALPHETTES, LAETITIA, CHEVALLIER, VALENTINE, COOL, VINCENT ADOLPHE CAROL, KOCHANOWSKI, NADINE
Format Patent
LanguageEnglish
Published 01.10.2020
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Summary:The present invention relates to methods for reducing the heterogeneity of a population of recombinant proteins produced in cell culture, said methods comprising growing host cells producing a recombinant protein in a cell culture medium wherein the cell culture medium comprises one or more cysteine/cystine analogs.
Bibliography:Application Number: US201816768091