OXADIAZOLE TRANSIENT RECEPTOR POTENTIAL CHANNEL INHIBITORS

and pharmaceutically acceptable salts thereof wherein A, X, R1, R4 and n are as defined herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds may b...

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Main Authors Chen, Huifen, Déry, Martin, Volgraf, Matthew, Sturino, Claudio, Beaumier, Francis, Villemure, Elisia, Lépissier, Luce, Constantineau-Forget, Lea, Larouche-Gauthier, Robin, Grand-Maître, Chantal, Terrett, Jack Alexander
Format Patent
LanguageEnglish
Published 01.10.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:and pharmaceutically acceptable salts thereof wherein A, X, R1, R4 and n are as defined herein. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.
Bibliography:Application Number: US202016903020