EXTRACELLULAR SECRETION OF TARGET PROTEIN
The present invention provides a method for effective extracellular secretion of a target protein, by preparing a fusion protein connecting LARDS to the target protein and having pI lowered by adjusting the overall charge of target protein, and by using ABC transporter of a bacterial type 1 secretio...
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Main Authors | , , |
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Format | Patent |
Language | English |
Published |
24.09.2020
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Subjects | |
Online Access | Get full text |
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Summary: | The present invention provides a method for effective extracellular secretion of a target protein, by preparing a fusion protein connecting LARDS to the target protein and having pI lowered by adjusting the overall charge of target protein, and by using ABC transporter of a bacterial type 1 secretion system (T1SS). The method can allows a protein be produced at a large amount simply and effectively without a separate purification process. |
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Bibliography: | Application Number: US202016811024 |