NEW CATALYTIC SYSTEM FOR SCALABLE PREPARATION OF INDOXACARB

It is an object of the present invention to provide a novel and advantageous process for commercially preparing of indoxacarb which is racemic or enantiomerically enriched at chiral center from its amide precursor using a new catalytic system. More particularly, it relates to an efficient method of...

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Bibliographic Details
Main Authors PILLAI, Bijukumar Gopinathan, VENKATARAMANA, Rajuri, BICIDI, Jayapal Reddy, MANNAM, Sreedevi
Format Patent
LanguageEnglish
Published 06.08.2020
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:It is an object of the present invention to provide a novel and advantageous process for commercially preparing of indoxacarb which is racemic or enantiomerically enriched at chiral center from its amide precursor using a new catalytic system. More particularly, it relates to an efficient method of preparation of indoxacarb which is racemic or enantiomerically enriched at chiral center from methyl-7-chloro-2,5-dihydro-2-[[[(4-trifluoromethoxy) phenyl]amino]carbonyl]-indeno[1,2-e][1,3,4]oxadiazine-4a(3H) carboxylate represented as formula (I) using methoxycarbonylation agent and metal salt of methylsulfinylmethylide in hydrocarbon solvent in the presence of organic base and phase transfer catalyst.
Bibliography:Application Number: US201816496961