OLIGOSACCHARIDE-PROTEIN CONJUGATES

Provided herein are conjugates comprising a protein and an oligosaccharide of one of Formulae I-VI. Also provided herein are pharmaceutical compositions comprising such conjugates. Further provided herein are methods of treating a lysosomal storage disorder in a mammal by administration of an oligos...

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Main Authors YOUNG, Lauren, ZHU, Yunxiang, STEFANO, James E, KUTZKO, Joseph P, PEER, Andreas, REARDON, Michael R, ZHENG, Xiaoyang, MILLER, Robert J, AVILA, Luis Z, KONOWICZ, Paul A, PAN, Clark Q, PATERSON, Duncan E, FINN, Patrick, HARRAHY, John, ZHOU, Qun
Format Patent
LanguageEnglish
Published 09.07.2020
Subjects
CHEMISTRY
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SUGARS
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Summary:Provided herein are conjugates comprising a protein and an oligosaccharide of one of Formulae I-VI. Also provided herein are pharmaceutical compositions comprising such conjugates. Further provided herein are methods of treating a lysosomal storage disorder in a mammal by administration of an oligosaccharide-glycoprotein conjugate.
Bibliography:Application Number: US201916581148