Encoded Solid Phase Compound Library with Polynucleotide Based Barcoding

• Main Authors: McEnaney, Patrick J, MacConnell, Andrew B, Kodadek, Thomas, Paegel, Brian M
• Format: Patent
• Language: English
• Published: 18.06.2020
• Subjects: BEER; BIOCHEMISTRY; CHEMISTRY; COMPOSITIONS THEREOF; CULTURE MEDIA; ENZYMOLOGY; METALLURGY; MICROBIOLOGY; MICROORGANISMS OR ENZYMES; MUTATION OR GENETIC ENGINEERING; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS; SPIRITS; VINEGAR; WINE

Provided herein are polynucleotide encoded chemical libraries comprising one or more bead members, wherein the beads comprise: a chemical moiety comprising a compound library member; a polynucleotide moiety comprising an oligonucleotide encoding the compound library member, and a barcode identifying...