Novel Alpha-Hydroxy Carboxylic Acid and Derivatives and Other GRAS-Based Amide and Imide Prodrugs of Amphetamine Compounds and Uses Thereof

The invention describes pharmaceutical compounds and compositions comprised of a ligand attached to stimulants (CNS drugs) in a manner that substantially decreases or deters the potential for stimulants abuse, addiction, illicit and illegal use, and overdose. These compounds and compositions find pa...

Full description

Saved in:
Bibliographic Details
Main Author Thottathil, John K
Format Patent
LanguageEnglish
Published 16.04.2020
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:The invention describes pharmaceutical compounds and compositions comprised of a ligand attached to stimulants (CNS drugs) in a manner that substantially decreases or deters the potential for stimulants abuse, addiction, illicit and illegal use, and overdose. These compounds and compositions find particular use in providing an abuse-resistant alternative treatment for certain disorders, such as attention deficit hyperactivity disorder (ADHD), ADD, narcolepsy, and obesity. When delivered at the proper dosage, the pharmaceutical composition provides therapeutic activity similar to that of the parent active agent.
Bibliography:Application Number: US201816603874