ANTI-NGF COMPOSITIONS AND USE THEREOF

The present invention is directed to antibodies and fragments thereof having binding specificity for NGF. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the VH, VL and CDR polypeptides described herein, and...

Full description

Saved in:
Bibliographic Details
Main Authors Stewart, Erica A, Dutzar, Benjamin H, Kovacevich, Brian R, Billgren, Jens J, McNeill, Patricia Dianne, Latham, John A, Chang, Betty Yu-Ching, Fan, Pei, Garcia-Martinez, Leon F, Mitchell, Danielle M, Ojala, Ethan W, Akatsuka, Corinne C
Format Patent
LanguageEnglish
Published 27.02.2020
Subjects
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online AccessGet full text

Cover

More Information
Summary:The present invention is directed to antibodies and fragments thereof having binding specificity for NGF. Another embodiment of this invention relates to the antibodies described herein, and binding fragments thereof, comprising the sequences of the VH, VL and CDR polypeptides described herein, and the polynucleotides encoding them. The invention also contemplates conjugates of anti-NGF antibodies and binding fragments thereof conjugated to one or more functional or detectable moieties. The invention also contemplates methods of making said anti-NGF antibodies and binding fragments thereof. Embodiments of the invention also pertain to the use of anti-NGF antibodies, and binding fragments thereof, for the diagnosis, assessment and treatment of diseases and disorders associated with NGF.
Bibliography:Application Number: US201916504602