BTK Inhibitors to Treat Solid Tumors Through Modulation of the Tumor Microenvironment

In certain embodiments, the invention includes therapeutic methods of using a BTK inhibitor to treat solid tumor cancers by modulation of the tumor microenvironment, including macrophages, monocytes, mast cells, helper T cells, cytotoxic T cells, regulatory T cells, natural killer cells, myeloid-der...

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Bibliographic Details
Main Authors Lannutti, Brian, Covey, Todd, Kaptein, Allard, Izumi, Raquel, Hamdy, Ahmed, Johnson, Dave, Ulrich, Roger, Barf, Tjeerd, Rothbaum, Wayne
Format Patent
LanguageEnglish
Published 19.12.2019
Subjects
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Summary:In certain embodiments, the invention includes therapeutic methods of using a BTK inhibitor to treat solid tumor cancers by modulation of the tumor microenvironment, including macrophages, monocytes, mast cells, helper T cells, cytotoxic T cells, regulatory T cells, natural killer cells, myeloid-derived suppressor cells, regulatory B cells, neutrophils, dendritic cells, and fibroblasts.
Bibliography:Application Number: US201916371592