Factor XIIa Inhibitors

The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIIa inhib...

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Bibliographic Details
Main Authors Taylor, Jerry A, Orth, Peter, Debenham, John S, Dahlgren, Markus K, McKittrick, Brian Alexander, Chu, Hong Dong, Wu, Zhicai, So, Sung-Sau, Sun, Zhongxiang, Whitehead, Brent R, Gable, Jonathan E, Lombardo, Matthew, Hicks, Jacqueline D, Lan, Ping, Bhat, Sathesh P, Bittner McCracken, Amy, Katipally, Revathi Reddy, Rao, Ashwin U
Format Patent
LanguageEnglish
Published 21.11.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Summary:The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIIa inhibitors.
Bibliography:Application Number: US201716461849