COMPOSITIONS AND METHODS FOR TREATING CDK4/6-MEDIATED CANCER
Methods for designing heterobifunctional small molecules which selectively degrade/disrupt CDK4/6 and compositions and methods of using such degraders/disruptors to treat CDK4/6-mediated cancer are provided.
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| Main Authors | , , , , , , , |
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| Format | Patent |
| Language | English |
| Published |
07.11.2019
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Methods for designing heterobifunctional small molecules which selectively degrade/disrupt CDK4/6 and compositions and methods of using such degraders/disruptors to treat CDK4/6-mediated cancer are provided. |
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| AbstractList | Methods for designing heterobifunctional small molecules which selectively degrade/disrupt CDK4/6 and compositions and methods of using such degraders/disruptors to treat CDK4/6-mediated cancer are provided. |
| Author | Jin, Jian Liu, Jing Xiong, Yan Karoulia, Zoi Wu, Xuewei Poulikakos, Poulikos Ahmed, Tamer Yang, Xiaobao |
| Author_xml | – fullname: Jin, Jian – fullname: Liu, Jing – fullname: Xiong, Yan – fullname: Poulikakos, Poulikos – fullname: Yang, Xiaobao – fullname: Wu, Xuewei – fullname: Karoulia, Zoi – fullname: Ahmed, Tamer |
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| Title | COMPOSITIONS AND METHODS FOR TREATING CDK4/6-MEDIATED CANCER |
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