CHROMATOGRAPHY METHOD

The present invention relates to a method for removal of large contaminants, such as virus, in a chromatographic process for purification of a target molecule, preferably monoclonal antibodies, mAbs, by using a specifically designed chromatographic bead having a thin outer layer and a core functiona...

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Bibliographic Details
Main Authors Maloisel, Jean-Luc, Palmgren, Ronnie, Lind, Ola, Noren, Bjorn
Format Patent
LanguageEnglish
Published 08.08.2019
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present invention relates to a method for removal of large contaminants, such as virus, in a chromatographic process for purification of a target molecule, preferably monoclonal antibodies, mAbs, by using a specifically designed chromatographic bead having a thin outer layer and a core functionalized with a ligand adsorbing the mAbs or parts thereof.
Bibliography:Application Number: US201916386628