COMPOUNDS USEFUL FOR ALTERING THE LEVELS OF BILE ACIDS FOR THE TREATMENT OF DIABETES AND CARDIOMETABOLC DISEASE

Described herein are compounds of Formula I or a pharmaceutically acceptable salt thereof. The compounds of Formula I act as Cyp8b1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for diabetes and cardiovascular disease.

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Bibliographic Details
Main Authors Tang, Haiqun, Verras, Andreas, Li, Derun, Walsh, Shawn P, Hruza, Alan, Dykstra, Kevin D, McCracken, Amy, Wu, Wen-Lian, Rao, Ashwin, Tagat, Jayaram, Cumming, Jared N, Lankin, Claire, Zhang, Tianyuan, Liu, Hong, Taoka, Brandon M, Caplen, Mary Ann, Caldwell, John P, McKittrick, Brian
Format Patent
LanguageEnglish
Published 18.07.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Summary:Described herein are compounds of Formula I or a pharmaceutically acceptable salt thereof. The compounds of Formula I act as Cyp8b1 inhibitors and can be useful in preventing, treating or acting as a remedial agent for diabetes and cardiovascular disease.
Bibliography:Application Number: US201716324604