FERMENTATION PROCESS FOR ANTIBODY PRODUCTION
A feedback control mechanism for a fermentation of yeast cells to make recombinant proteins uses a respiratory quotient measurement which adjusts the levels of oxygenation and/or fermentable sugar feed. The feedback control mechanism permits well controlled cultures that produce good amounts of prod...
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Main Authors | , , , |
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Format | Patent |
Language | English |
Published |
11.07.2019
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Subjects | |
Online Access | Get full text |
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Summary: | A feedback control mechanism for a fermentation of yeast cells to make recombinant proteins uses a respiratory quotient measurement which adjusts the levels of oxygenation and/or fermentable sugar feed. The feedback control mechanism permits well controlled cultures that produce good amounts of product while avoiding toxic accumulation of ethanol. Additionally, recombinant proteins so produced have excellent qualitative properties, such as excellent homogeneity and proper inter-subunit assembly. |
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Bibliography: | Application Number: US201916258014 |