MEK Inhibitors and Methods of Their Use

Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods...

Full description

Saved in:
Bibliographic Details
Main Authors Koltun, Elena S, Bussenius, Joerg, Curtis, Jeffry Kimo, Kennedy, Abigail R, Blazey, Charles M, Peto, Csaba J, Tsang, Tsza H, Anand, Neel Kumar, Aay, Naing, Kim, Angie Inyoung, Joshi, Anagha Abhijit, Bowles, Owen Joseph, Costanzo, Simona, Dubenko, Larisa, Rice, Kenneth D, DeFina, Steven Charles, Manalo, Jean-Claire Limun
Format Patent
LanguageEnglish
Published 16.05.2019
Subjects
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online AccessGet full text

Cover

More Information
Summary:Disclosed are compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof. Such compounds are MEK inhibitors and are useful in the treatment of proliferative diseases, such as cancer. Also disclosed are pharmaceutical compositions containing such compounds as well as methods of using the compounds and compositions of the invention in the treatment of cancer.
Bibliography:Application Number: US201815952923