METHOD FOR PREPARING GLUCAGON-LIKE PEPTIDES

The present invention refers to a method for preparing a glucagon-like peptide, comprising precipitation of the peptide or of a precursor peptide by means of mixing with an anti-solvent comprising diisopropyl ether and acetonitrile. Further, the present invention also relates to a peptide conjugated...

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Bibliographic Details
Main Authors LOIDL, Guenther, NEUHAUS, Benjamin, SCHOENLEBER, Ralph O, STADELMAIER, Andreas
Format Patent
LanguageEnglish
Published 04.04.2019
Subjects
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
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Summary:The present invention refers to a method for preparing a glucagon-like peptide, comprising precipitation of the peptide or of a precursor peptide by means of mixing with an anti-solvent comprising diisopropyl ether and acetonitrile. Further, the present invention also relates to a peptide conjugated to a solid phase and a pharmaceutical composition comprising a Liraglutide peptide obtainable from a method according to the present invention.
Bibliography:Application Number: US201716086460