ASSAYS FOR MASSIVELY COMBINATORIAL PERTURBATION PROFILING AND CELLULAR CIRCUIT RECONSTRUCTION

The present invention provides tools and methods for the systematic analysis of genetic interactions, including higher order interactions. The present invention provides tools and methods for combinatorial probing of cellular circuits, for dissecting cellular circuitry, for delineating molecular pat...

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Main Authors Shalek, Alexander K, Cong, Le, Dixit, Atray, Rozenblatt-Rosen, Orit, Norman, Thomas, Adamson, Brittany, Gaublomme, Jellert, Parnas, Oren, Regev, Aviv, Cleary, Brian, Lander, Eric S, Weissman, Jonathan
Format Patent
LanguageEnglish
Published 21.03.2019
Subjects
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS OR TEST PAPERS THEREFOR
COMPOSITIONS THEREOF
CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES
CULTURE MEDIA
ENZYMOLOGY
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROCESSES OF PREPARING SUCH COMPOSITIONS
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Summary:The present invention provides tools and methods for the systematic analysis of genetic interactions, including higher order interactions. The present invention provides tools and methods for combinatorial probing of cellular circuits, for dissecting cellular circuitry, for delineating molecular pathways, and/or for identifying relevant targets for therapeutics development.
Bibliography:Application Number: US201815965192